- 1 The Main Preventive Steps of Colon Cancer.
- 2 Major Prevention Factors of Colon Cancer.
- 3 FDA (Food and Drug Administration of the United States of America).
- 4 Chemo-prophylaxis.
- 5 Aspirin & Other NSAID Drugs.
- 6 Folic Acid.
- 7 Calcium.
- 8 Estrogen Replacement Therapy.
The Main Preventive Steps of Colon Cancer.
We should not be relieved if there is not such a great risk of Colorectal cancer. Even the small risk can be minimized. The only simple step is to provide regular preventive control. So if cancer detected early it is more easily treatable. Preventive control can also show colon cancer by identifying any existing polyps that are a precancerous condition. The risk reduced by daily exercise, weight control, nutrition change and Chemo-prophylaxis.
Major Prevention Factors of Colon Cancer.
Colonoscopy is the endoscopic examination of the extensive inside and the distal piece of the little gut with a CCD camera or a fiber optic camera on an adaptable cylinder went through the butt. It can give a visual determination (e.g., ulceration, polyps) and stipends the open door for biopsy or expulsion of suspected colon malignant growth injuries. Colonoscopy can expel polyps as little as one millimeter or less. Due to the fact that most colon cancers start as polyps, colonoscopy helps in diagnosis and removal of these. A major research in the USA shown that colonoscopy reduces the risk of cancer by 75%. Because polyps do not cause symptoms, it is good to discover them. Most colon cancers begin as polyps. Less than 1% of total polyps converted to cancers. There is no way to identify which ones are developing into cancers. The removal of polyps done during colonoscopy.
Research of Nurse’s Health Study in America has shown that physical exercise reduces the risk of women developing cancer by half. Other studies have shown similar benefits from exercise for both women and men. The researchers who conducted the Nurse’s Health Study found that walking 3 miles per hour for an hour a day offers the same degree of protection as cycling or swimming for half an hour. Based on these studies, researchers estimate that more than 15% of all cancers of the colon are prevented by half an hour of walking.
The best nutritional advice is to reduce the consumption of red meat in order to reduce the risk. There are no other nutritionally confirmed medical advice and other scientific data. For many years an article saying that fiber-rich diet, such as fruits and vegetables and antioxidant vitamins, helps prevent cancer. Protective effects of the fibers supported for two decades of barren research. More recent studies have shown that there is no correlation between these foods and ingredients and cancer. The first major study that demonstrated the absence of correlation is Nurse’s Health Study. 90000 women monitored for 16 years, and the results published in the reputable New England Medicine magazine in 2000. A second study published in the Lancet magazine at the same time and confirmed the absence of protective action.
FDA (Food and Drug Administration of the United States of America).
Subsequently, following the publication of the above studies, the FDA announced to the dietary supplements industry not sell products that claim that fiber reduces the risk of cancer.
Studies for the Continuous Consumption of Fruits and Vegetables.
In this regard, recent studies have been exploring early results on whether continued fruit and vegetable consumption helps major prevention factors of colon cancer. Although fiber is nutritious and can contribute to the prevention of other cancers, neither the study of Health Professionals Follow Up have shown that they have any protective role against colon cancers. As far as antioxidant vitamins are concerned, the results of recent studies are confusing. 3 major medical studies (Nurse’s Health Study), Physicians’ Health Study, and Alpha Tocopherol – Beta Carotene Cancer Prevention Study) did not show a protective effect of taking B-carotene or vitamin A, C, or E.
Studies With a Positive Effects on Protection.
Convincing evidence against the protective role of antioxidant vitamins. Clinical study involving individuals with a history of colon Adenomas. Researchers randomly divided 864 study participants into 4 groups. One group received B-carotene, a second vitamin C and E, the third a combination of the previous ones, and the fourth received no treatment (placebo treatment). Each participant underwent a colonoscopy after one year and then after 4 years. There was no difference between the four groups in Adenoma growth. Nevertheless, there have been some indications that taking large amounts of vitamin D reduces the risk of carcinoma. Medical study Nurse’s Health Study showed that women who consumed more than 550 IU of vitamin D had a 60% lower risk of developing cancer than women who received less vitamin amount. But the results were not so strong as to allow scientists to recommend vitamin D as a precautionary measure.
Chemo-prophylaxis is not the same as Chemotherapy. Chemo-prevention is the use of drugs or vitamins and natural supplements to prevent cancer. Chemo-prophylaxis is at the heart of some of the most promising Colorectal cancer research. Several studies show that people taking such supplements or Folic acid and Non-Steroidal Anti-Inflammatory (NSAID) have reduced chances for colon cancer than those who do not receive such treatment.
What it Means Non-Steroidal Anti-Inflammatory Drugs?
Non-Steroidal Anti-Inflammatory drugs are a medication class that diminish torment, decline fever, avoid blood clusters and, in higher portions, decline irritation. Reactions rely upon the particular medication, however to a great extent incorporate an expanded danger of gastrointestinal ulcers and drains, heart assault and kidney malady. There is no evidence that these major prevention factors of colon cancer really contribute to the prevention. However, the correlation is so strong that doctors now advise on taking some. The following table shows the main drugs of this category.
|NSAID Generic Name||Common Brand Name||How It Is Given||Form Of Medication|
|Naproxen||Naprosyn||By Mouth Twice Daily||Liquid or Tablet|
|Ibuprofen||Advil – Motrin||By Mouth 3-4 Times Daily||Liquid or Tablet|
|Indomethacin||Indocid||By Mouth 3 Times Daily||Liquid or Tablet|
|Diclofenac Sodium||Voltaren||By Mouth Once or Twice Daily||Tablet|
|Piroxicam||Feldene||By Mouth Once Daily||Tablet|
|Celecoxib||Celebrex||By Mouth 3 Times Daily||Tablet or Dissolvable Tablet.|
Multi Vitamin Formulas.
Various cancer prevention centers around the world recommend multi-vitamin formulations of dietary supplements as a precautionary measure for all, regardless of individual risk. Before taking any dietary supplement, it is advisable to consult your doctor. You and your doctor have to take into account the main benefits in terms of potential dangers and always in relation to individual medical history. For example, if you suffer from an ulcer, taking aspirin or others may aggravate the condition. Women entering or in Menopause should take into account the benefits of hormone replacement therapy against the known risks of breast cancer. Research is currently underway to clarify whether any of the drugs really contribute to major prevention factors of colon cancer.
Aspirin & Other NSAID Drugs.
Aspirin and other Non-Steroidal Anti-Inflammatory drugs are the most studied factors for Chemo-prophylaxis and the major prevention factors of colon cancer. Doctors noted that people taking analgesics for Rheumatoid Arthritis are less at risk than the general population. NSAIDs are protective, inhibit enzymes and mediate many physiological functions in the body. They also affect Tumor growth. It is likely that NSAID’s prevent the development of colon cancer and other unknown paths.
A series of studies conducted in 1983 showed that Clinoril, used to treat arthritis, reduced the size and number of polyps in individuals with Familial Adenomatous Polyposis. More recently, a 2000 study in the New England Journal of Medicine showed that people with the same illness received 400mg of Celebrex for 6 months, had fewer polyps than untreated patients. There are currently no studies comparing the effectiveness of Clinoril – Celebrex – Aspirin. Every benefit of these drugs is temporary, because after 3 months and stopping the medication, the number and size of the polyps increased. Long-term intake of these drugs causes ulcers and other problems of the digestive system.
Research of Nurse’s Health Study showed that women who received multivitamin supplements for at least 15 years had a 75% lower chance of developing colon cancer than women who did not receive it. This protective benefit appears to be closely related to Folic Acid. In the study, women who received 400 mg or more, daily, had the greatest benefit. Other studies shown a protective effect for men as well. The mechanism by which the Folic Acid protects against colorectal cancer is unknown. The result is better for people who have a genetic predisposition for colon cancer.
The positive effect is also greater among people who take Folic Acid dietary supplements than those who receive Folic Acid alone from food. On the contrary, foods rich in acid such as fruits and vegetables do not seem to affect the risk of cancer. Some Physicians recommend taking daily multivitamin preparations because they contain higher amounts of Folic Acid than food. As a conclusion, taking multivitamin supplements seems to act as protective against major prevention factors of colon cancer.
Most studies show that people who consume bigger amounts of calcium either with food or with supplements have a lower risk of cancer. It should be noted that not all studies showed significant difference. In a study done in 1999 in England Journal of Medicine, 930 patients with a history of Colorectal Adenoma randomized and received either 1200 mg of calcium or placebo therapy. The research had a duration of one year and again four years later. Individuals in the group receiving Calcium have less chance of developing new Adenomas. The study considers that the protective effects of calcium start early, before polyps converted into cancers. Calcium probably reduces the levels of bile and fatty acids in the digestive tract associated with colorectal cancer. These chemicals are found in the Bowel and inhibit the abnormal growth of cancer.
Estrogen Replacement Therapy.
Estrogen supplements taken by women to reduce the symptoms of Menopause, reduce the risk of cancer. However, this benefit should be assessed in relation to a mild increase in the risk of breast cancer. In a study of Nurse’s Health Study 59002 menopausal women receiving hormone replacement therapy had a 44% reduction in cancer risk compared to those who did not receive. Estrogens seem to help in several ways on the major prevention factors of colon cancer. One is the reduction in the production of Insulin-like growth factor IGF-1. Another factor affects colon and rectal cells. If you are thinking about receiving this kind of treatment, discuss your options with your doctor regarding your individual risk factors.
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